Journal of Investigative Dermatology

Back to Broad? How Molecular Profiling Facilitates Targeted Therapies of Overlapping Phenotypes

Kilian Eyerich, Natalie Garzorz-StarkFirst published: 14 September 2023 AbstractPsoriasis and eczema are noncommunicable inflammatory skin diseases (ncISDs) that may present with overlapping clinical and histopathological features, making their differential diagnosis a pertinent challenge for clinicians. Treatments with highly effective mAbs for psoriasis and eczema are increasingly replacing broadly acting immunosuppressant drugs such as methotrexate and

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Back to Broad? How Molecular Profiling Facilitates Targeted Therapies of Overlapping Phenotypes
Journal of Investigative Dermatology

Gene Expression-Based Molecular Test as Diagnostic Aid for the Differential Diagnosis of Psoriasis and Eczema in Formalin-Fixed and Paraffin-Embedded Tissue, Microbiopsies, and Tape Strips

Felix Fischer, Anais Doll, Deniz Uereyener, Sophie Roenneberg, Christina Hillig, Lucca Weber, Verena Hackert, Martin Meinel, Ali Farnoud, Peter Seiringer, Jenny Thomas, Philipp Anand, Larissa Graner, Franziska Schlenker, Roland Zengerle, Pontus Jonsson, Manja Jargosch, Fabian J Theis, Carsten B Schmidt-Weber, Tilo Biedermann, Michael Howell, Kristian Reich, Kilian Eyerich, Michael Menden, Natalie Garzorz-Stark, Felix Lauffer, Stefanie

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Gene Expression-Based Molecular Test as Diagnostic Aid for the Differential Diagnosis of Psoriasis and Eczema in Formalin-Fixed and Paraffin-Embedded Tissue, Microbiopsies, and Tape Strips
JDDG

Clinical Letter: Psoriasis or eczema? One-year results from the DGUV research project FB323 with application of the Molecular Classifier in occupational dermatoses

Philipp Bentz, Kilian Eyerich, Elke WeisshaarFirst published: 26 September 2022 Dear Editors, hand eczema is a complex and multifactorial skin disease, for which treatment remains challenging . The most im-portant differential diagnosis is psoriasis. An exact diag-nosis is often not possible, due to a similar clinical picture. Moreover, dermatopathohistological analysis often cannot distinguish between the

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Clinical Letter: Psoriasis or eczema? One-year results from the DGUV research project FB323 with application of the Molecular Classifier in occupational dermatoses
medRxiv

Gene expression based molecular test proves clinical validity as diagnostic aid for the differential diagnosis of psoriasis and eczema in formalin fixed and paraffin embedded tissue

May 22, 2022: Highly specific and efficient drugs have been developed during the last two decades to treat non-communicable chronic inflammatory skin diseases (ncISD).

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Gene expression based molecular test proves clinical validity as diagnostic aid for the differential diagnosis of psoriasis and eczema in formalin fixed and paraffin embedded tissue
Microsystems and Nanoengineering

Eliminating viscosity bias in lateral flow tests

Daniel M. Kainz, Bastian J. Breiner, Susanna M. Früh, Tobias Hutzenlaub, Roland Zengerle & Nils PaustFirst published: 06 September 2021 AbstractDespite the widespread application of point-of-care lateral flow tests, the viscosity dependence of these assay results remains a significant challenge. Here, we employ centrifugal microfluidic flow control through the nitrocellulose membrane of the strip to

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Eliminating viscosity bias in lateral flow tests
Analyst

RespiDisk: a point-of-care platform for fully automated detection of respiratory tract infection pathogens in clinical samples

Markus Rombach , Sebastian Hin , Mara Specht, Benita Johannsen , Jan Lüddecke a Nils Paust , Roland Zengerle , Louis Roux , Thomas Sutcliffe , Johannes R. Peham , Christopher Herz , Marcus Panning , Oliver Donoso Mantke and Konstantinos MitsakakisFirst published: 02 September 2020 AbstractWe present the RespiDisk enabling the fully automated and

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RespiDisk: a point-of-care platform for fully automated detection of respiratory tract infection pathogens in clinical samples